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Peer-Reviewed Publications

Every Claim.Independently Validated.

ExoDisc™ performance data comes from independent researchers and leading journals, not internal testing alone.

EV Recovery Comparison

Unparalleled Yield

Head-to-head comparison of EV recovery rates across isolation methods, based on published data.

ExoDisc™~95%
Size Exclusion40-70%
Precipitation30-60%
Ultracentrifugation5-25%

Source: Woo et al., ACS Nano 2017; Cho et al., Theranostics 2019

~95%

EV recovery

From biosamples, validated by independent researchers using NTA and protein quantification.

ACS Nano, 2017

<5%

inter-assay CV

Reproducibility across independent labs and operators, surpassing all conventional methods.

Theranostics, 2019

~20x

higher yield

Compared to ultracentrifugation, the previous gold standard for EV isolation.

Published data

Publications

Key Publications

ACS Nano2017

ExoDisc for Rapid, Size-Based Exosome Isolation and Protein Biomarker Analysis

Woo HK, Sunkara V, Park J, et al.

Original ExoDisc paper demonstrating centrifugal microfluidic EV isolation from biosamples with ~95% recovery. Established the technical foundation for the platform.

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Theranostics2019

Fully Automated, Label-Free Isolation of Extracellular Vesicles from Whole Blood for Cancer Diagnosis and Monitoring

Sunkara V, Kim CJ, Park J, et al.

Validated ExoDisc performance for clinical sample types. Demonstrated inter-disc CV <5% and suitability for downstream biomarker analysis.

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ACS Appl Mater Interfaces.2023

Exosome Precipitation by Ionic Strength Modulation: ExoPRISM

Sunkara V, Park J, Han J, et al.

Comparative study of EV isolation methods. Contextualized ExoDisc's performance advantages over precipitation-based approaches.

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Lab Chip2024

Tonicity-induced cargo loading into extracellular vesicles

Lee C, Kumar S, Park J, Choi Y, Clarissa EM, Cho YK.

Demonstrates ExoDisc as an EV drug loading platform. Enables EV-based therapeutic development using standardized isolation.

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JoVE2022

Extracellular Vesicle Uptake Assay via Confocal Microscope Imaging Analysis

Kim CJ, Kuczler MD, Dong L, et al.

Step-by-step validated protocol for EV uptake studies using ExoDisc-isolated vesicles. Used in academic and translational research settings.

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IOVS2024

Isolation and Characterization of Extracellular Vesicles Through Orthogonal Approaches for the Development of Intraocular EV Therapy

Leung J, Pollalis D, Nair GKG, et al.

Demonstrates ExoDisc use in ophthalmology translational research. Validates compatibility with clinical investigational workflows for stem cell-derived EV therapeutics.

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Technology

Centrifugal Microfluidics

ExoDisc uses lab-on-a-disc technology. Centrifugal force drives sample fluid through size-selective microfluidic channels; no pumps, valves, or external pressure required.

As the disc spins, sequential filtration stages separate EVs (30-200 nm) from larger particles, cell debris, and free proteins. The single-use cartridge eliminates cross-contamination risk.

The result: highly purified EVs in a standardized buffer, delivered reproducibly in under 30 minutes from any standard biological fluid.

Researcher loading sample into ExoDisc cartridge with a pipette
Loading a sample into the ExoDisc™ cartridge

Questions About Our Data?

Our science team is ready to discuss protocols, validation data, and integration support.