ExoDisc™ automates exosome isolation from biosamples in under 30 minutes, delivering up to ~20x higher yield than ultracentrifugation, with <5% inter-assay CV.
Published in ACS Nano, Theranostics, and Analytical Chemistry.
Specifications
Plasma, Urine, Cell Culture Media, Serum
1-4 mL per channel
Purified EVs in PBS
<30 minutes
6 samples per disc
~95%, Fully Automated
Performance
All data from peer-reviewed publications. ¹² View sources
| Feature | ExoDisc™ | Ultracentrifugation | Precipitation Kits | Size Exclusion |
|---|---|---|---|---|
| EV Recovery | ~95%¹ | 5-25% | 30-60% | 40-70% |
| Processing Time | <30 min | 3-5 hours | 1-2 hours | 2-4 hours |
| Inter-assay CV | <5%² | 20-40% | 15-30% | 10-20% |
| Purity | High | High | Low | High |
| Training Required | None | Extensive | Minimal | Moderate |
| Equipment Cost | Low | High | Low | Moderate |
| Throughput | 6 samples/run | 1-6 tubes | Variable | 1 sample/column |
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Applications
ExoDisc™ is independently validated in peer-reviewed literature, from veterinary clinics to oncology labs.
In-clinic EV isolation from PRP and biosamples for regenerative and wound-healing protocols.
Clinical workflowsBiomarker discovery, liquid biopsy, and EV biology studies at leading research institutions worldwide.
Published in ACS NanoEV-based drug delivery, cargo loading, and QC workflows for therapeutic development pipelines.
Adv. Healthcare Mater.Standardized sample preparation for EV-based assay development with <5% inter-assay CV across sites.
Theranostics validatedWorkflow
No ultracentrifuge. No chromatography column. No specialized training required.
Pipette 1-4 mL of plasma, serum, urine, or cell culture media into the ExoDisc cartridge.
Place the cartridge in LabSpinner. Centrifugal microfluidics drives size-selective filtration; no pumps, no valves.
Retrieve purified EVs (30-200 nm) in under 30 minutes, ready for NTA, RNA-seq, proteomics, or Western blot.
Yield
~95%
EV recovery
Evidence
Every performance claim on this page is backed by independent, peer-reviewed research.
Woo HK, Park J, Cho JH, et al.
Original ExoDisc paper demonstrating centrifugal microfluidic EV isolation from biosamples with ~95% recovery. Established the technical foundation for the platform.
View Paper (opens in new tab)Cho H, Kim J, Jeon M, et al.
Validated ExoDisc performance for clinical sample types. Demonstrated inter-disc CV <5% and suitability for downstream biomarker analysis.
View Paper (opens in new tab)Sunkara V, Ha HK, Kim SC, et al.
Comparative study of EV isolation methods. Contextualized ExoDisc's performance advantages over precipitation-based approaches.
View Paper (opens in new tab)Support
Plasma, serum, urine, cell culture media, and other biological fluids. Validated across clinical and research sample types in peer-reviewed publications.
NTA, TEM, Western blot, RNA-seq, proteomics, ELISA, and other standard EV characterization methods. Published compatibility data available in our Science section.
ExoDisc delivers ~95% EV recovery vs. 5-25% with UC, with <5% inter-assay CV vs. 20-40% for UC. Processing takes <30 min vs. 3-5 hours, with no specialized training required.
The LabSpinner benchtop device is purpose-built for ExoDisc cartridges; no additional centrifuge or equipment needed. Low equipment cost compared to ultracentrifuges.
Email sales@labspinner.com or use the contact form on our Contact page. We respond within 1-2 business days with quotes, technical information, and protocol support.
~95% EV recovery vs. 5-25% with ultracentrifugation, with less than 5% CV across independent labs.
